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Subsequently, cytochromes P450 (CYP79s) catalyzes the conversion of the amino acid derivatives to aldoximes, oxidized later by CYP83s into nitrile oxides, transformed to thiohydroximates via glutathione (GSH) S-transferases (GSTFs) and the C-S lyase (SUR1) reaction, and finally converted to the GL core structure by S-glucosyltransferases (UGT74s) and sulfotransferases (SOTs) (Figures 35)
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Seek immediate emergency care (call 999 or go to A&E) if you experience symptoms of a severe allergic reaction after a B12 injection, such as difficulty breathing, facial or throat swelling, widespread rash, or dizziness
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Wear appropriate personal protective equipment including gloves, lab coat, and protective eyewear
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