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Development of SGLT1 and SGLT2 inhibitors

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The study participants included 28 men who received once-weekly 2.5 mg tirzepatide for 4 weeks, followed by once-weekly 5 mg tirzepatide plus lifestyle change for the remainder of the study

For individuals with BMI above 40 or 50, the difference between 20% and 28% weight loss can be the difference between still being classified as obese and reaching a healthy weight range