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16 weeks 8-12 vials ~112 daily doses
Nov 2018;46(11):4624-4633
Synthesis From the starting material phenol, paracetamol can be made in the following manner: Phenol is nitrated using sulfuric acid and sodium nitrate (as phenol is highly activated, its nitration requires very mild conditions compared to the oleum-fuming nitric acid mixture required to nitrate benzene)
The cofactors FAD and FMN, which include vitamin B2, are transferred to an electron by the enzyme methionine synthase reductase (MTRR) during the subsequent reactivation cycle
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