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This peptide is characterized by three ionizable groups: the carboxylic group (p K a 2.64), the amino group of the -alanine residue (p K a 9.49), and the imidazole ring in histidine (p K a 7.04), with the p K a of the whole molecule being 8.27 (Bertinaria et al

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FIGURE 1 Study on the relationship between trace elements and clinical efficacy of ALL Once in a therapeutic trial, children with acute lymphoblastic leukemia treated with chemotherapy were divided into two groups: chemotherapy plus zinc + ferrum and chemotherapy alone, and the time required to start and complete remission was significantly shorter in the chemotherapy plus zinc + ferrum group than in the chemotherapy alone group

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