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The diagnostic criteria for IC/BPS, based on the proposed guidelines of the European Society for the Study of Interstitial Cystitis, constituted chronic pelvic pain, pressure, or discomfort perceived to be related to the urinary bladder accompanied by at least one other urinary symptom, such as persistent urge to void or urinary frequency, for more than 6 months, and the exclusion of potentially similar diseases 11,25

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The semaglutide versus tirzepatide side effects comparison shows that tirzepatide generally produces less nausea than pure GLP-1 agonists at equivalent weight loss levels

For manufacturers, it provides a reliable foundation for formulation

Arch Gen Psychiatry 57 : 6573

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