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Supplementing with L-carnitine can help close this nutritional gap by supporting efficient fat oxidation, cellular energy production, and mitochondrial functionparticularly during physical activity
This intervention helps protect cardiolipin and mitochondrial DNA from further oxidative destruction
Pentostatin also can inhibit RNA synthesis, cause DNA strand breaks, disrupt ATP-dependent cellular processes, and inhibit adenosylhomocysteinase (S-adenosylhomocysteine hydrolase), all of which also may contribute to the drug's lymphocytotoxic effects
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Choi et al., 2024)
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