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While glutathione is a powerful antioxidant and theoretically could reduce oxidative stress in melanocytes, there is no robust clinical data showing that increasing dietary or supplemental glutathione can reliably prevent or reverse gray hair in humans. The bodys regulation of hair pigmentation is complex, he added, and once melanocytes lose their ability to produce pigment, antioxidants alone are unlikely to restore it

M., Brower, M., & Hoehse, M

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Minor impurities or unreacted structural fragments within a peptide sample can skew experimental data, lead to failed cell cultures, or create volatile results

doi: 10.1016/j.imlet.2005.11.007 179 NortonRLFredericksGJHuangZFayJDHoffmannFWHoffmannPR