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For the timepoint study ( n = 50), male and female APOE-TR mice were euthanized at three different timepoint (10-, 25-, and 50-weeks) for three homozygous genotypes: APOE2-TR, APOE3-TR, and APOE4-TR (Supplementary Table S1)

Compared to other technologies, LC-MS/MS offers high specificity, selectivity, and a wide dynamic range, making it less susceptible to interference and applicable across various biological matrices

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2 weeks before basketing, 5 consecutive days

Each vial contains 2,667 mg of pure L-Carnitine in liquid form

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