tirzepatide diabetes trial shows additional 21.1% weight loss following intensive lifestyle intervention Weight-loss jab Mounjaro trial begins

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People who choose saturated fats may not get the cardiovascular benefits of a keto diet due to elevated cholesterol levels

or (ii) RCTs comparing different AOMs with active drug control

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The SURMOUNT-1 and SURPASS-5 trials summarize weight loss and glycemic benefits, again, both associated with reduced risk and progression of DN, but this study does not present direct clinical trial evidence of tirzepatide improving established neuropathy [41, 42]

Common options include topical brightening agents, chemical peels, laser treatments, and oral supplements