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This is due to a lack of intrinsic factor

Maternal depression and antidepressant use during pregnancy and the risk of autism spectrum disorder in offspring

The addition of glycine provides building blocks for protein synthesis at a time when dietary protein intake often decreases

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[1] In practice, 1 mL (which provides the full 100 mg of B and B, etc.) is a common dose for general supplementation in deficient states, but clinicians may start with lower volumes for mild deficiencies or in smaller patients