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Retatrutide and cagrilintide are both investigational drugs not approved by the FDA
The drug efflux pump MDR1 promotes intrinsic and acquired resistance to PROTACs in cancer cells
Several medical treatments, including drugs and procedures, are available, but often not very effective
This makes the estrogen even easier to remove from the body, making it safe to be excreted
The safety assessment is based on the independent safety profiles of each compound (GLP-1 medications through extensive FDA trials, BPC-157 through decades of preclinical research), their non-overlapping mechanisms, and growing clinical experience from physicians who prescribe both
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