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Known as the sleep hormone, melatonin is, more specifically, a neurochemical secreted by the pineal gland in the brain in response to the nighttime absence of light

Biochemical investigations showed a normal level of cysteinyl glycine in plasma, an abnormal urinary profile with increased excretion of cysteinyl glycine (4972 mmol/mol of creatinine) and leukotrienes with increased leukotriene D4 and complete absence of LTE4

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Elevated calcium levels activate calpains and other calcium-dependent enzymes, which impair mitochondrial function and contribute to neuronal injury

Mar 24 2021;26(7)doi:10.3390/molecules2607182