The Precision Peptide Genetic Test (available for $298) maps your genetic predispositions across 49 peptides and 14 metabolic pathways, including genes linked to thyroid-related weight gain and GLP-1 receptor sensitivity
Its stated general range for GLP-1 users is around 1.2 to 1.6 grams per kilogram daily, against roughly 0.8 for sedentary adults generally
2014;127(Pt 11:238390
In line with our short-term metabolic analyses, previous studies in New Zealand obese and diet-induced obese male mice suggested that GLP1/E acts primarily at central levels to reverse metabolic alterations by decreasing food intake and body weight, while the potential beneficial effects on pancreatic beta-cells were possibly secondary and indirectly-mediated 33,48
This observation led to the development of (Pro3)GIP, an analog of GIP with a glutamic-acid-to-proline substitution at position 3, improving glucose homeostasis and preventing weight gain in animal models of diabetes and obesity (Sparre-Ulrich et al., 2016)
Nausea and vomiting are common during pregnancy, with Though ginger may help reduce this unpleasant pregnancy complication, more research is needed to identify the maximum safe dosage