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This is consistent with broader findings that specific probiotic strains, such as Lactobacillus acidophilus LA5 and Lacticaseibacillus rhamnosus GG, can attenuate periodontitis-induced bone resorption and enhance bone regeneration by modulating the gut microbiota and circulating metabolites ( Akkermansia muciniphila , which is often reduced in periodontitis, demonstrates potent anti-inflammatory effects
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Bacteroidetes neurotoxins and inflammatory neurodegeneration
The reduction in the flavoprotein MTHFR activity observed in individuals with the variant MTHFR 677TT genotype leads to an increase in plasma homocysteine (14)
Intravenous and even intranasal glutathione have both shown promising results in restoring cognitive function in neurodegenerative diseases
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