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Mechanism involves NO system modulation (homeostatic regulationupregulating when deficient, moderating when excessive), VEGF/VEGFR2 upregulation for angiogenesis, FAK-paxillin pathway activation for cell migration (40% increase per Chang et al.), and EGR-1 transcription factor upregulation for growth factor sensitivity
Multiple experiments indicate that GCL is the rate-limiting enzyme in the plant glutathione biosynthesis (Foyer et al., 1995, 1997
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Guest Editors Martha E Sosa Torres and Peter M.H.Kroneck
Downey, CA
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