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Simultaneous quantification of TB-500 and its metabolites in in-vitro experiments and rats by UHPLC-Q-Exactive orbitrap MS/MS and their screening by wound healing activities in-vitro

oryzae (Xoo) gives rise to devastating crop losses in rice

Retatrutide also reduced biomarkers associated with liver inflammation and fibrosis progression

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Since we did not detect a decrease in pyruvate in the cortex (Supplementary Table 7), these results could suggest there may be reduced lactate dehydrogenase activity in astrocytes, as lactate can be produced downstream from glucose to support energy needs in neurons