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Compared with individuals in the metformin and second- or third-line glucose-lowering medications groups, major CVEs were significantly lower in individuals with NAFLD and type 2 diabetes who received GLP-1RAs but not different from those who received SGLT2 inhibitors
Patients without insurance face the highest costs, paying $1,200+ per month for brand medications
Step down to tirzepatide or semaglutide with a one-week washout
Semaglutide is supplied as a lyophilized powder in sealed vials, reconstituted with bacteriostatic water for laboratory use
