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For many patients, gastrointestinal side effects, including sulfur burps, diminish significantly after 8-12 weeks as physiologic adaptation occurs

7 Initiating and monitoring If adding a DPP-4 inhibitor to sulfonylurea, meglitinide or insulin therapy, consider whether a dose reduction of the sulfonylurea/meglitinide/insulin is needed to reduce hypoglycaemia risk

Review about each risk of bias item for each included study

These complementary effects on fat and muscle catabolism suggest that GLP-1 RAs may help preserve skeletal muscle integrity while concurrently improving metabolic efficiency in the context of obesity-related muscle dysfunction

Its half-life is short (7 minutes) because it is rapidly cleaved by dipeptidyl peptidase-IV (DPP-IV) after residues 2-3

Will I Lose Muscle Or Gain Fat After Stopping