BMC cardiovascular disorders 14, 88 (2014)
Food & Drug Administration (FDA) has issued multiple safety warnings, while Byetta lawsuits accused manufacturers of failing to warn about these risks
1).29,32 With respect to the vascular system, rGLP-1 activation induces modest decreases in blood pressure,33,34 it has a vasodilator effect, improves arterial stiffness, and prevents atherosclerotic plaque formation-and has plaque stabilizing effects-through its anti-inflammatory and antiapoptotic effects as demonstrated in animal models.29,32,3538 Despite controversies about rGLP-1 expression in vascular smooth muscle and endothelial cells, studies have shown that arGLP-1 has antiproliferative effects on these cells,39 reduces oxidative stress, improves endothelial function, and increases nitric oxide production in experimental models.3540 In the heart they produce a discrete increase in heart rate (24 beats/min), although this does not seem to be associated with an increase in arrhythmias or cardiovascular events
Hypoglycemia: Only a concern if you're also on insulin or sulfonylureas
Step 3: Use consistently for 3 month to see effective results
Getting reconstitution right matters because errors compound