As a result, the FDA granted an additional indication for Wegovy to reduce the risk of major cardiovascular events in March 2024
It says comprehensive evaluation including cardiovascular assessment, baseline labs, and psychiatric screening where indicated should come first
Of note, many of these cases exhibit CSF oligoclonal bands, Gd-enhancing lesions on MRI and clinical response to immunosuppressionall features very typical of MSindicating that secondary immune responses to a primary trigger can play a significant role in the final clinical phenotype
The shift from injectable to oral administration would dramatically expand access and adherence
However, evidence-based algorithms guiding when and how to initiate GLP-1 RAs postoperatively are currently lacking
Matek D, Sikiric P, et al