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Pregnancy as a window to future health: excessive gestational weight gain and obesity

L-Carnitin ist eine nicht-essentielle aminosurehnliche Verbindung, die fr den Transport von langkettigen Fettsuren zu den Mitochondrien der Zelle verantwortlich ist, wo aus der Oxidation von Fett Energie gewonnen wird

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Low v-ATPase-inhibition increases m and enhances cell fitness under mitochondrial mistranslation in multiple cell-types and mitochondrial disease patient-derived fibroblasts To confirm that the suppressed cell growth defect under ACT-induced mistranslation was due to v-ATPase deficiency, we used the highly selective v-ATPase inhibitors concA and bafA on WT cells

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Sikiric et al., 2020b)