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(5) We multiplied the V max of g-cystathionase (CTGL) by 1/3.5

The dose escalation schedules differ between the two medications: Semaglutide Dose Escalation Weeks 14: 0.25mg weekly (initiation dose) Weeks 58: 0.5mg weekly Weeks 912: 1.0mg weekly Weeks 1316: 1.7mg weekly Week 17+: 2.4mg weekly (maintenance dose for weight loss) Tirzepatide Dose Escalation Weeks 14: 2.5mg weekly (initiation dose) Weeks 58: 5mg weekly Weeks 912: 7.5mg weekly (many patients maintain here) Weeks 1316: 10mg weekly Weeks 1720: 12.5mg weekly Week 21+: 15mg weekly (maximum dose) Not every patient needs to reach the maximum dose and at BlueWater Wellness Center, we don't escalate for the sake of it

V., Piepho, H

FDA-Approved Semaglutide Options in 2026: Popular GLP-1 Options for Weight Loss By 2026, semaglutide is available through multiple FDA-recognized pathways, offering patients and providers greater flexibility in treatment selection

Furthermore, the lyophilised format ensures long-term stability during storage and transport

It is of critical importance that future studies directly evaluate sex-specific effects of these compounds to fully assess their clinical potential