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Andrea Corona Altimmunes GLP-1 drug shows positive results for alcohol use disorder On Tuesday, Altimmune announced topline data from their Phase 2 RECLAIM trial showing that pemvidutide, an investigational balanced glucagon/GLP-1 dual receptor agonist, significantly reduced the number of heavy drinking days compared to placebo in patients with moderate to severe alcohol use disorder

4 Gut microbiota-derived metabolites and depression Bacterial compounds found in the gut can enter the bloodstream affect brain regions and can interact with nearby gut components like hormonal cells or neurons, which can subsequently send signals to the brain (161)

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The review situates Dihexa within the renin-angiotensin systems central nervous system arm, summarizes the HGF/c-Met activation hypothesis, and surveys behavioral pharmacology in rodent cognitive models