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7 People who experience the following should not use Zoloft: Seizures Liver problems Manic behavior or manic depression Closed-angle glaucoma Bleeding in the digestive tract Serotonin syndrome This is not an exhaustive list

While canonical UCP1-mediated thermogenesis does not appear to be engaged at the mRNA level, we cannot exclude the possibility of post-translational modulation of UCP1 activity 42,43