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Low levels can lead to weakened immunity, skin issues, hormonal imbalance, and sluggishness
& Muoz, E
For instance, in NSCLC, treatment with first- and second-generation EGFR tyrosine kinase inhibitors (TKIs) often leads to the development of the EGFR T790M mutation, while third-generation inhibitors subsequently select for the C797S mutation, both of which confer resistance
10.1046/j.1471-4159.1995.64051965.x J
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