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At the higher doses, results were very consistent: All participants lost at least 5% of their body weight Around 3 in 4 lost 15% or more With placebo, only around 1 in 4 lost 5% or more Phase 3 update (TRIUMPH-4, 68 weeks, topline results) In December 2025 , Eli Lilly shared early (topline) results from a larger phase 3 study (TRIUMPH-4)

The association between changes in adiposity during the first 20 weeks and subsequent MACE risk was assessed

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In a pilot study involving humans, supplemental glutathione was associated with an improved recovery marker [10] and decreased fatigue after aerobic exercise

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