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Green tea EGCG inhibits DNMTs leading to hypomethylation of the tumour suppressor gene promoters (e.g., p16, RAR) and re-expression of pro-apoptotic genes as well as it interferes with RTK signalling NF-B activation that are associated with inflammatory and proliferative signals (16)
EGT) is a sulfurised and tri- N -methylated histidine derivative, which exists in a tautomeric state between both the thione (Figure 4) and thiol forms and has demonstrable antioxidant properties
This unique mechanism makes it a promising option for metabolic health support
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MDC1 collaborates with TopBP1 in DNA replication checkpoint control
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