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Because of this, it has been studied for many years

It can help with: Improved brain health Help with depression Stronger immune system Better mental clarity Increased energy Support for bone health You may need a B12 shot a few times each month until your vitamin levels are normal and stable

Reduced appetite and smaller portions is pretty much the aim of treatment

Contact your healthcare provider immediately if you experience severe, persistent abdominal pain, particularly if it radiates to the back, as this may indicate pancreatitis

J Hepatol 2015

Conditions include alcoholic liver disease, viral hepatitis, cirrhosis, and primary or metastatic liver cancer Renal dysfunction : Impaired kidney function reduces B12 elimination, causing accumulation even with normal intake Haematological conditions : Myeloproliferative neoplasms, chronic myeloid leukaemia, polycythaemia vera, and hypereosinophilic syndrome increase transcobalamin production, elevating total serum B12 Laboratory interference : Macro-B12 (immunoglobulin-bound B12) and assay interference can cause spuriously elevated results without true excess In clinical practice, unexplained hypercobalaminaemia should prompt investigation for underlying disease, particularly in patients without obvious supplementation history