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[2] [12] There is no established link between B12 supplementation and weight loss in individuals with normal B12 levels

Sublingual (under-the-tongue) forms dissolve in your mouth, theoretically enhancing absorption by allowing some B12 to enter the bloodstream through mucous membranes rather than relying solely on digestive uptake

The oral daily dose far exceeds the vitamin requirement because the normal transporter protein-mediated absorption is absent, leaving only very inefficient intestinal passive absorption

For data analysis, we used R, and for data visualization, Prim Plus (version 84) was utilized

These modifications stabilize the molecular structure, allowing it to mimic the amphipathic alpha-helix of the native hormone

Those following a vegan or strict plant-based diet are more likely to suffer from vitamin B12 deficiency