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Essential for protein synthesis and DNA production, contributing to cell growth and division
66 The CT-2A malignant mouse astrocytoma responded to CR when grown orthotopically or subcutaneously in C57BL/6J mice despite its PTEN and TSC2 deficiency, and constitutive AKT activation
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TB-500, a synthesized fragment, mirrors many of TB4's systemic repair properties and is known to distribute broadly throughout the body, supporting healing across multiple tissue types simultaneously
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Methods: A transverse aortic constriction (TAC) model of myocardial hypertrophy was established in vivo using C57BL/6 mice, while neonatal murine cardiomyocytes were stimulated with phenylephrine (PE) as an in vitro validation model system
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