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Conclusion Macrophage-derived PGRN and possibly other Grn products play a critical role in the development of HFD-induced obesity, tissue inflammation, and impaired hormonal signaling in both central and peripheral metabolic organs
Nutrition: Follow a nutrient-dense, calorie-appropriate diet with adequate protein to help preserve lean mass
Automation of the CHARMM General Force Field (CGenFF) I: bond perception and atom typing
10.1016/j.redox.2015.08.006 98 MatsushitaM.FreigangS.SchneiderC.ConradM.BornkammG
153 Complementing MDR1-mediated drug efflux, the multidrug resistance-associated protein (MRP) subfamily comprises nine members (MRP19) that confer resistance through partially distinct yet overlapping mechanisms