In April 2005 the US Food and Drugs Administration (FDA) approved a synthetic version, called exenatide, to treat type 2 diabetic patients unable to sufficiently control their blood sugar levels with other diabetic medications like metformin, and sulfonylureas
Front Pharmacol 5:196
When the gut lining becomes compromised, it can lead to a wide range of issues including inflammation, poor digestion, and systemic health disruptions
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2 Events related to a clinical picture of altered skin sensation such as sensitive skin, hyperesthesia, dysesthesia and paresthesia were reported by a higher proportion of participants, and at a higher rate, in the Wegovy HD arm (22%), compared to treatment with Wegovy 2.4 mg (6%) and placebo (0.3%)