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Ultimately, it is biologically plausible that by mimicking the actions of GLP-1 Ozempic could have positive effects on both cravings and brain health
In fact, many patients find that having a small, protein-rich meal a few hours before the shot helps stabilize their stomach
Injection site affects absorption rate and peak concentration but does not fundamentally change how the medication works
BMJ , e075354
However, 13-week Phase 2 data in 125 patients cannot be meaningfully compared to 68-week Phase 3 data in 1,961 patients
In 2009, Richard DiMarchi and Matthias H Tschp's team reported that dual agonists targeting GLP-1R/GCGR did better in weight loss compared to GLP-1RA [10]
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