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The activation of GLP-1R triggers a complex intracellular signaling cascade, which at the end activates protein kinase A (PKA) pathway via production of cyclic adenosine monophosphate (cAMP) ( GLP-1 exerts potent glucose-lowering effects through multiple mechanisms including insulin release stimulation and suppression of glucagon secretion
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Therefore, it is important to maintain adequate levels of glutathione through a balanced diet and lifestyle or through supplements if necessary
Nat Rev Mol Cell Biol (2001) 2:13845.10.1038/35052082 76 NakamuraFStosselTPHartwigJH
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