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A large observational study or registry would be needed to fully rule it out, but given how uncommon MTC is (1 in 50k maybe) and how many have now taken GLP-1 RAs (millions), likely any major signal would have emerged by now
The Result: The nerve is simultaneously starved of energy (no ATP), stripped of insulation (no myelin), and suffocated (poor blood flow)
On obesity alone they make a huge differenceresulting in about 15 to 20 percent weight loss in randomized trials
Get emergency help if you have dark tarry stools and severe pain, fainting, or signs of shock
Treat "Tirzepatide vs Qsymia: GLP-1 vs Phentermine/Topiramate" as a way to pressure-test a decision before money, medication, or provider access is involved
Set realistic expectations Harbstreet says its important to manage expectations you can do all of the above and still put weight back on
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