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Kim JI, Choi JY, Lee DH, Choi TY, Lee MS, Ernst E

Interacts with inhibitory neurotransmission pathways: Sleep onset and maintenance rely on balanced excitatory and inhibitory neurotransmission

Pregnenolone sulfate modulation of N-methyl-D-aspartate receptors is phosphorylation dependent

For systemic research, certain contraindications exist, such as pregnancy, breastfeeding, active cancer, or conditions like Wilsons disease (a genetic disorder causing copper accumulation)

Midorikawa S, Sanada H, Hashimoto S, and Watanabe T (2000)

Injectable (IV/IM) glutathione has much higher bioavailability than oral forms, since it bypasses digestion, and is generally more effective for brightening