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Additionally, these compounds modulate cellular redox status, either through ROS generation (as seen with CAPE and EVO) or through antioxidant effects (demonstrated by RSV and CUR)

Among these, three pivotal epigenetic eventsDNA methylation, histone acetylation, and ncRNAplay essential roles in reshaping chromatin structure and dynamic repositioning of cis-regulatory elements, including promoters and enhancers, phenomena often observed in inflammatory conditions

However, its levels can drop with age, stress, a poor diet, and toxins

Exploiting transcription factors to target EMT and cancer stem cells for tumor modulation and therapy

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Edited by Dr Gerry Melino Rights and permissions Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made