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Evidence snapshot: The strongest human evidence comes from a 2-year randomized controlled trial in 65 healthy older adults (Nass et al., 2008, Annals of Internal Medicine) showing sustained GH/IGF-1 increases and preserved fat-free mass, plus an earlier short-term human polysomnography study on sleep (Copinschi et al., 1997, Neuroendocrinology, PMID 9349662)
Vitamin B12 supplements are recommended to population groups at higher risk for developing vitamin B12 deficiency: everyone (no matter what their diet) over 50 years old, people with diseases of the gastrointestinal system such as Chrohns and IBS, women on oral contraceptives and people who regularly use nitrous oxide or are alcoholics
Please consult your physician or pharmacist or product package for more information
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10.1242/jcs.03229 J
cardiovascular problems including hypertension, myocardial infarction and oxidation of cholesterol
