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[Mayo Clinic] Ghasemian M, Owlia S, Owlia MB
Gallstone disease was also linked with the long-term use of GLP-1 agonist drugs
The upregulated Pt transporters [e.g., organic cation transporters (OCTs), multidrug and toxin extrusion proteins (MATEs), and copper transporters 1/2 (Ctr1/2)] in DGR increase the accumulation of Pt drugs in peripheral nerves as the first step to induce PIPN (Sprowl et al., 2013
Both raise the body's own growth hormone (GH) in a pulsatile way rather than injecting synthetic GH directly
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Los agonistas GLP-1 pueden producir elevaciones modestas de la frecuencia cardaca, aunque la relevancia clnica es incierta.Paradjicamente, estos frmacos han demostrado reducir eventos cardiovasculares mayores en poblaciones de alto riesgo
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