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Due to its role in sleep regulation and stable profile, DSIP is suitable for extended research where recovery, stress balance, and neurological support are key areas of interest

Shared decision-making between patients and clinicians should weigh cardiovascular benefits against cost, adverse effects, and individual treatment goals

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Diagnostic modalities utilizing CRCs altered metabolism such as 18F-fluorodeoxyglucose positron emission tomography (18F-FDG PET/CT) and metabolomic analysis of circulating metabolites, improved early detection through enhanced sensitivity and specificity

doi: 10.1016/j.molmed.2021.04.009 128 DarbyTMNaudinCRLuoLJonesRM