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Studies have shown a higher prevalence of residual gastric contents in GLP-1RA users, prompting professional societies to issue perioperative management guidelines

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Peter Attia, on his April 2026 AMA covering peptides, placed BPC-157 in what he called "bucket number one": peptides characterised by uncertain origins, broad claims, weak mechanistic evidence, and failure to replicate animal data in humans [4]

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The major contribution of this study is the strengthening of evidence to support the control of patients with pyroglutamic acidosis, in addition to proposing PyroGlu as a way to measure oxidative stress