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10.2 Mechanisms and epidemiology Nociplastic pain stems from central sensitization, involving abnormal pain processing in the peripheral and central nervous systems, leading to increased sensitivity and reduced inhibition

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Routes and technique matter Injection route intramuscular versus subcutaneous and sterile technique matter for safety and comfort

In the future, with increased scientific research investment, its application scenarios will be further expanded

The physiological complexity of GLP-1 entails glucose homeostasis, gastrointestinal motility, and the release of insulin and glucagon

BMJ Open Diabetes Res Care