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However, when intracellular iron ions are overloaded, Fe 2+ can catalyze the generation of metabolically toxic reactive oxygen species and phospholipid peroxide through the Fenton reaction, leading to cell damage or death (Ingold et al., 2018) (Figure 4)

The peptide also enhances the expression of brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF), critical molecules for neuronal survival and plasticity

The role of the iron protoporphyrins heme and hematin in the antimalarial activity of endoperoxide drugs

Its very good for a milder type of lupus, and its been shown to improve overall survival rates in lupus patients