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Research has shown reduced melanin levels compared to placebo groups, though results vary based on metabolism, dosage, and absorption
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So in 2014, the FDA began approving these medications for weight loss first Saxenda (liraglutide) , then Wegovy (semaglutide) , Zepbound (tirzepatide) , and most recently, Foundayo (orforglipron)
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Since then, several more GLP-1 agonists have been approved by the FDA
