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Evolved proteases triggered robust cell death across multiple cancer cell lines

Pioglitazone, a diabetes medication, may benefit selected patients with biopsy-proven NASH, but is also specialist-led and off-label , with potential risks including weight gain, fluid retention, heart failure, and increased fracture risk

After therapy, sickle cell disease won't cause health crises

The investigators identified adults with CKD stage 3 or later and T2DM who were newly prescribed either a GLP-1RA or a dipeptidyl peptidase-4 inhibitor (DPP4i) between January 2015 and December 2020

What Should Patients Do

The findings were consistent after accounting for age, race, ethnicity, body mass index (BMI), breast density, and diabetes