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Involvement of Bcl-2 family members, phosphatidylinositol 3'-kinase/AKT and mitochondrial p53 in curcumin (diferulolylmethane)-induced apoptosis in prostate cancer

Metabolic adaptation is most likely the reason for this plateau [11] rather than poor response or resistance to the medication

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The key is managing expectations: these are supportive tools, not pharmaceutical replacements