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HTN: hypertension, BP: blood pressure, SBP: systolic blood pressure, DBP: diastolic blood pressure, FMD: Flow-Mediated Dilation, CVD: cardiovascular, CKD: chronic kidney disease, MDA: Malonyl dialdehyde
Rosen DR, Siddique T, Patterson D, Figlewicz DA, Sapp P, et al
For patients with Long COVID or ME/CFS, practitioners often recommend starting with a smaller dose (e.g., 1/4 or 1/2 scoop) to assess tolerance, as rapid detoxification can sometimes cause a temporary exacerbation of symptoms (a Herxheimer reaction) as toxins are mobilized
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It gives you a stream of benefits over a longer period
Liver disease Liver disease can inflame, damage, or disrupt your liver's ability to filter toxins, produce bile, and manage metabolism
When plotted, the 4 mg starting dose produces noticeably higher initial concentrations than starting at 2 mg, which is why the trial data showed more early gastrointestinal effects in the higher starting dose group
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