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Although biochemically separated from the GSH system, the Trx system shares NADPH as a common reducing cofactor and serves as an alternative pathway for reducing disulfide bonds, making this system especially relevant if the GSH system has been compromised or rendered dysfunctional (Silva-Adaya et al., 2014)

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The 2,000 g may be divided into twice-daily 200 g injections, or once-daily 400 g injections, five days per week, with two days off to aid the recovery of the anterior pituitary receptors

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