Indeed, in clinical practice, metformin demonstrated a variety of beneficial effects on menstrual disorder, anovulation, androgen excess, insulin resistance, and cardiovascular risk, whereas its weight loss effect is often inconsistent and transient [21, 22]
Patients using these medications have shown significant weight loss, often ranging from 10% to 15% or more of their initial body weight, when combined with lifestyle interventions [1] [10]
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2023 Nov;67(22):e2300195
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2 Weight and mood: a connected relationship Theres a well-established link between obesity and mental health conditions like depression