The Downsides: Risks, Side Effects, and Concerns Despite the headline-making results, GLP-1 drugs are not without side effects or controversy
It is pharmacological modulation of reward circuitry, and it is one of the most profound effects of GLP-1 therapy that clinical trials rarely capture in their data
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However, this adverse effect did not result in an increase in cardiovascular events in dedicated randomized trials [7,8]
Patients are increasingly learning about emerging therapies through social media, podcasts, influencers, online communities, and direct-to-consumer marketing
This makes it one of the most effective pharmaceutical weight loss interventions ever studied